Akademiliv

Sahlgrenska akademins nyheter

På Svenska
University of Gothenburg Logotype
  • News
  • Notices
  • Calendar
  • Grants
  • About Akademiliv
The illustration on the cover of the thesis (Mother of pearl) was made by Martina Vesik.

New thesis: Higher risk of future accidental bowel leakage after sphincter injury

3 February, 2023 Leave a Comment

THESIS. A study that was part of a recent doctoral thesis at the Institute of Clinical Sciences reports a significantly higher risk of developing gas and fecal incontinence among women who suffer an anal sphincter injury during childbirth.

On February 10, Ida Nilsson will defend her doctoral thesis in obstetrics and gynecology. The thesis explores the long-term effects of anal sphincter injuries suffered during childbirth. The title of the thesis is: The long-term effects of obstetrical anal sphincter injury on pelvic floor function (Link to the thesis in GUPEA).

Preventing sphincter injury during childbirth reduces theprevalence, severity, and impact on quality of life due to accidental bowel leakage ,and can also delay the onset ofaccidental bowel leakage. A national action plan resembling the one introduced in Norway in 2004 seems to be effective in reducing the frequency of such injuries and maintaining a low frequency.

Pelvic floor dysfunction is an umbrella term for a number of conditions, including urinary incontinence, fecal incontinence, and pelvic organ prolapse. It is a major global health problem for women of all ages, but particularly among the elderly. The most important risk factor for future pelvic floor disorders is having had a vaginal birth.

Ida Nilsson.

“The thesis examines the effects on pelvic floor function 20 years after childbirth with or without anal sphincter injury, and with or without a vacuum extractor” says Ida Nilsson, a resident physician in gynecology and obstetrics at the Women’s Clinic at Södra Älvsborg Hospital in Borås.

Two million women in four countries

Women included in component papers I, II, and IV of the thesis were recruited from the Swedish Medical Birth Register and answered a questionnaire about current pelvic floordisorders. All had given birth to one or two children about 20 years before answering the questionnaire. The study groups included women with no sphincter injury, women with one sphincter injury, and women who had sphincter injuries in two out of two deliveries.

Paper III examines the incidenceof sphincter injury among nearly two million women, from the Canadian, Norwegian, Swedish, and Austrian birth registers. The study examined vaginal first-time mothers, with or without an obstetrical vacuum extractor or forceps delivery and with or without a previous cesarean section, between 2004 and 2016.

Long-term effects of anal sphincter injuries at childbirth

“Fecal and gas leakage in women without sphincter injury and with one or two sphincter injuries” – CI, confidence interval; OASI, obstetrical anal sphincter injury. From Nilsson et al. Symptoms of fecal incontinence two decades after no, one, or two obstetrical anal sphincter injuries. Am J Obstet Gynecol 2021 Mar;224:276.e1-.e23 (and page 42 of the thesis).

Some of the main research findings are listed below:

  • Having a sphincter injury entails a very high risk of fecal incontinence two decades after birth.
  • The prevalence, severity, and self-perceived impact of gas and fecal incontinence increased after one and two sphincter injuries.
  • The incidence of sphincter injury was three times higher after a delivery with a vacuum extractor compared to a delivery without a vacuum extractor and also after a first delivery with a sphincter injury.
  • There appeared to be considerable potential for lowering the incidence of OASI, since the incidence varied widely among the four countries studied.

Ida Nilsson believes that the results in her thesis indicate that introducing a national action plan with regular and structured education and training of all categories of staff in the delivery wards could be decisive in reducing the incidence of sphincter injuries.

“The long term follow-up time that we have in our studies, from the sphincter injury to the evaluation of the pelvic floorsymptoms, is largely unique. And the results can be helpful for women, midwives, and obstetricians when planning a birth after a previous sphincter injury.”

This underscores the importance of all women being well informed and able to take responsibility for their own choice of birth method.

BY: SUSANNE LJ WESTERGREN

INFORMATION OM THE DEFENCE OF DOCTORAL THESIS

Time: February 10, 2023, 09:00–11:30
Location: Arvid Carlsson Auditorium, Academicum, Medicinaregatan 3, Gothenburg

The defense of thesis will be presented partly in Swedish and partly in English

Principal supervisor: Maria Gyhagen
Assistant supervisor: Ian Milsom
External reviewer: Katariina Laine, University of Oslo, Norway
Examining committee: Christina Bergh, Hans Törnblom, and Eva Uustal

 

By: Elin Lindström
Tagged With: avhandling

Leave a Comment Cancel reply

Your email address will not be published. Required fields are marked *

Add your own events in the Akademiliv Calendar

Registration for supervisors – no later than April 14th

Information from Sahlgrenska Academy Research Support Office

[UPDATED FEB 22]
The Sahlgrenska Academy Research Support Office provides an overview of upcoming and current calls, nominations and events in an information letter. This letter is updated approximately four times per semester.

’20 minutes for researchers’ is back – see full spring program

During 20 minutes over Zoom, the Biomedical Library gives tips on tools and services that can facilitate your research everyday life.

We are building at Medicinareberget

You will now find comprehensive information on construction projects that affect the Sahlgrenska Academy in the Staff Portal.

Lunch menus

Café Anatomen
Menu not available on website.

Café Annedal
Menu not available on website.

Lunchen.nu

Lustgården på Änggårdsbacken
Take away for external guests between 11.00-12.30 weekdays.

Lyktan

Mersmak Mölndal

Mersmak Sahlgrenska

Mersmak Östra

Salt & Syra

More news

Effective treatment in rare but deadly form of cancer

21 March, 2023

NEW STUDY. An advanced surgical therapy has proved considerably more efficacious than conventional treatments for patients with melanoma in the …  

Kidney research highlighted in discussions at the Royal Palace of Stockholm

20 March, 2023

COLLABORATION. Professor Jenny Nyström was one of four kidney researchers recently invited to the Royal Palace of Stockholm, where Prince Daniel …  

For all researchers – web-based course on research ethics

16 March, 2023

RESEARCH ETHICS. The seven faculties of medical sciences in Sweden have jointly developed a web-based, English-language course on research …  

Dean and Pro Dean elections: time to nominate candidates

14 March, 2023

DEAN ELECTIONS. Sahlgrenska Academy’s Drafting Committee now invites all employees to nominate candidates for the roles of Dean and Pro Dean d …  

Nominate for Sahlgrenska Academy’s Educational Award 2023 – deadline May 5th

13 March, 2023

NOMINATE. Do you know of teachers who have developed and implemented a successful and innovative educational idea in teaching? Or one or more …  

Mapping outdoor environments for older adults

13 March, 2023

RESEARCH WITH IMPACT. There are no rules governing access to the outdoors and nature experiences for older adults at residential care facilities …  

Groundbreaking research on individually tailored precision medicine for treating lung cancer

13 March, 2023

GRANTS. The prognosis for lung cancer is worse than most cancer types, but development of new treatments is advancing quickly. Volkan Sayin and …  

New episode of Akademiliv podcast – Autism overdiagnosed, Christopher Gillberg warns

10 March, 2023

PODCAST. Stop over diagnosing autism. Start looking at “the whole person”. These are messages from Professor Christopher Gillberg, a leading exp …  

Jan Lötvall honored for cell-to-cell communication discovery

10 March, 2023

PRIZE. Professor Jan Lötvall of the University of Gothenburg is receiving, as the first Swede to do so, the Lipid Science Prize — a personal aw …  

Strong interest in our Master’s Programme in Public Health Science

10 March, 2023

EDUCATION. The Master’s Programme in Public Health Science has been included in the top 10 list of the most sought-after international master’s pr …  

More news...

Sahlgrenska Academy

© University of Gothenburg
PO-Box 100, S-405 30 Gothenburg, Sweden
Phone: 00 46 31 786 0000

About the website

Elin Lindström is editor for Akademiliv.
Please feel free to send your ideas and comments to akademiliv@gu.se

Sign up for the Akademiliv newsletter:

Send you tips to Akademiliv

Do you have a suggestion for news, grants, seminars or an education?
Send an email to Elin Lindström Claessen