NEW STUDY. A research group at the University of Gothenburg has developed a method that makes the exact binding sites of specific proteins in the genome discernible. The method is based on the idea that DNA damage induced by ultraviolet (UV) light can change where proteins bind. The method is now published in the journal Nature Communications. Kerryn Elliott, a researcher in Erik Larsson Lekholm’s group at the Department for…
Exercise seems to protect against major brain hemorrhage
NEW STUDY. Regular physical activity and exercise may reduce bleeding in individuals with intracerebral hemorrhage, a University of Gothenburg study shows. The researchers emphasize the importance of physical activity to protect the brain. The study, published in the journal Stroke and Vascular Neurology, analyzed data on 686 people treated for intracerebral hemorrhage at Sahlgrenska University Hospital in Gothenburg during the years 2014 to 2019. The results are based on a…
Pediatric clinical studies’ underfunding risk
NEW STUDY. A clinical study with children as participants entails extra costs often omitted in the initial budget. Clinical studies involving children are thus at risk of being undercompensated, new research shows. Kids will be kids when they take part in clinical studies, as at other times. Sometimes they need a break to do something else for a while before the next study session can start. With children as study…
Physical activity crucial for poststroke recovery
NEW STUDY. After a stroke, physical activity can be pivotal to successful recovery. People who spend four hours a week exercising after their stroke achieve better functional recovery within six months than those who do not, a University of Gothenburg study shows. The study, now published in the scientific journal JAMA Network Open, is based on data concerning 1,500 stroke patients in 35 Swedish hospitals. The participants were grouped according…
Potency drug reduced long-term blood sugar in type 2 diabetes
NEW STUDY. A small group of patients with type 2 diabetes significantly improved their long-term blood sugar levels when treated with high-dose tadalafil, a medication used to treat erectile dysfunction. The result from the University of Gothenburg pilot study is striking, but repetition in a larger study and over a longer period is needed. Tadalafil is one of the active pharmaceutical substances known as PDE5 (phosphodiesterase type 5) inhibitors, a…