No registration required.
Welcome to the Sahlgrenska Academy Science Seminars, a series of seminars on Thursdays at 15-16 (OBSERVE, This time at 9-10). This seminar will be conducted in Assembly room Birgit Thilander at Academicum and online through zoom webinar.
Here is the link to the webinar: https://gu-se.zoom.us/j/64507245711
The seminars are open to anyone interested in taking part of scientific breakthroughs and projects in the medicine and health science field. Scientists, students and other staff from GU, VGR and other organisations with the common interest of medicine and health science, welcome!
Speaker: Karin Strijbis, Utrecht University, Netherlands
The mucosal surfaces of our body are colonized by commensal bacteria that stimulate healthy intestinal barrier properties. Pathogens on the other hand have evolved virulence factors to overcome the mucosal barrier and invade the intestinal epithelium. Transmembrane mucins are a family of highly glycosylated proteins with barrier and signaling potential, but what are their functions in the intestinal epithelium? In this lecture, I will present our latest (surprising) insights into microbe-mucin interactions and their impact on mucosal health and disease.
Karin Strijbis is a group leader and head of the Infection Biology group at Utrecht University. She did her PhD at the Amsterdam Medical Center where she studied metabolic adaptation of fungal pathogen Candida albicans. She was a postdoc with Hidde Ploegh at the Whitehead Institute of MIT in Cambridge, USA, during which she focused on innate immunology and receptor signaling. In 2014, she started her own group at Utrecht University and initiated a new research line on bacterial infections at mucosal surfaces and the functions of transmembrane mucins. She was awarded an ERC starting grant to determine how commensal and pathogenic bacteria interact with transmembrane mucins in the intestinal tract and a collaborative Dutch ZonMW grant to study the impact of vaginal microbiota on HIV infections. With her research group, she is aiming for a molecular understanding of microbe-host interactions and the development of therapeutics that benefic mucosal health.
Host: Thaher Pelaseyed, Dep. of Biomedicine, SA
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